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Failed Experiment ReportOpen accessMedicine

Survival, neurocognitive function, and health-related quality of life outcomes after rituximab-methotrexate, BCNU, teniposide, and prednisolone for primary CNS lymphoma: Final results of the HOVON 105/ALLG NHL 24 study.

Bromberg JEC; Issa S; van der Holt B; van der Meulen M; Dirven L; Minnema MC; Seute T; Durian M · 2024 · Neuro-oncology

WASTE classifies this as Failed Experiment Report · AI classification, approximate

An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

Background Studies on the efficacy of rituximab in primary CNS lymphoma (PCNSL) reported conflicting results. Our international randomized phase 3 study showed that the addition of rituximab to high-dose methotrexate, BCNU, teniposide, and…

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Metadata source: Europe PMC · DOI 10.1093/neuonc/noad224