Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally advanced hypopharynx and base of tongue cancer
Sung Hee Lim; Jong-Mu Sun; Joohyun Hong; Dongryul Oh; Yong Chan Ahn; Man Ki Chung; Han-Sin Jeong; Young-Ik Son · 2021 · The Korean Journal of Internal Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
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Abstract
Background/Aims Clinical trials have not consistently supported the use of induction chemotherapy (IC) for locally advanced head and neck squamous cell cancer. Hypopharynx and base of tongue (BOT) cancer has shown relatively poor survival. We investigated the role of IC in improving outcome over current chemoradiotherapy (CRT) in patients with hypopharynx and BOT cancer. Methods Treatment-naïve patients with stage III/IV (M0) hypopharynx or BOT cancer were randomly assigned to receive CRT alone (CRT arm: cisplatin 100 mg/m2 on D1 3-weekly, two times plus radiotherapy 68.4 Gy/30 fractions on we
Abstract by Sung Hee Lim; Jong-Mu Sun; Joohyun Hong; Dongryul Oh; Yong Chan Ahn; Man Ki Chung; Han-Sin Jeong; Young-Ik Son, The Korean Journal of Internal Medicine (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3904/kjim.2019.161