Microbiome modulation of tumorigenesis and immune responses
Yuning Chen; Ying Fang; Zibai Lyu; Yanxin Tian; Siyue Niu; Yan-Ruide Li; Lili Yang · 2026 · Journal of Biomedical Science
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The microbiome has emerged as a critical, context-dependent regulator of tumorigenesis and anticancer immunity, capable of either promoting cancer progression or protecting against malignancy. This dual role is mediated by multiple interconnected mechanisms-including chronic inflammation, modulation of immune responses, and alterations in host metabolic signaling. These microbiome-cancer interactions vary across organs, influencing malignancies in the colon, breast, lung, and beyond. Clinically, the microbiome significantly affects patient responses to cancer therapies, particularly immunother
Abstract by Yuning Chen; Ying Fang; Zibai Lyu; Yanxin Tian; Siyue Niu; Yan-Ruide Li; Lili Yang, Journal of Biomedical Science (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12929-025-01208-9