Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: Safety, efficacy, biomarker, and pharmacokinetics—CheckMate 908
Ira J. Dunkel; François Doz; Nicholas K. Foreman; Darren Hargrave; Álvaro Lassaletta; Nicolás André; Jordan R. Hansford; Tim Hassall · 2023 · Neuro-Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: Therapeutic options are limited in pediatric CNS malignancies. CheckMate 908 (NCT03130959) is an open-label, sequential-arm, phase 1b/2 study investigating nivolumab (NIVO) and NIVO + ipilimumab (IPI) in pediatric patients with…
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Metadata source: OpenAlex · DOI 10.1093/neuonc/noad031