Neural protein gamma-synuclein interacting with androgen receptor promotes human prostate cancer progression
Junyi Chen; Jiao Li; Chuanliang Xu; Yongwei Yu; Zhensheng Zhang; Chang Zheng; Zhen Deng; Yinghao Sun · 2012 · BMC Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Gamma-synuclein (SNCG) has previously been demonstrated to be significantly correlated with metastatic malignancies; however, in-depth investigation of SNCG in prostate cancer is still lacking. In the present study, we evaluated the role of SNCG in prostate cancer progression and explored the underlying mechanisms. METHODS: First, alteration of SNCG expression in LNCaP cell line to test the ability of SNCG on cellular properties in vitro and vivo whenever exposing with androgen or not. Subsequently, the Dual-luciferase reporter assays were performed to evaluate whether the role of
Abstract by Junyi Chen; Jiao Li; Chuanliang Xu; Yongwei Yu; Zhensheng Zhang; Chang Zheng; Zhen Deng; Yinghao Sun, BMC Cancer (2012) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/1471-2407-12-593