Sexual dimorphism in the complete Drosophila male central nervous system connectome
Stuart Berg; Isabella R. Beckett; Marta Costa; Schlegel Philipp; Michał Januszewski; Elizabeth C. Marin; Aljoscha Nern; Stephan Preibisch · 2026 · Cell
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Sex differences in behavior exist across all animals, typically under strong genetic regulation. In Drosophila, fruitless/doublesex transcription factors identify dimorphic neurons, but their organization into functional circuits remains unclear. We present the connectome of the entire Drosophila male central nervous system. This contains 166,700 neurons spanning the brain and nerve cord, fully proofread and annotated, including fruitless/doublesex expression and 11,710 neuron types. We provide the first comprehensive comparison between male and female brain connectomes to synaptic resolution,
Abstract by Stuart Berg; Isabella R. Beckett; Marta Costa; Schlegel Philipp; Michał Januszewski; Elizabeth C. Marin; Aljoscha Nern; Stephan Preibisch, Cell (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.cell.2026.08.015