SREBP1 Transactivation of NHE3 Impairs Cardiac Contraction and Aggravates Heart Failure.
Gu; Wen; Liu; Xue; Zhao; Zhao; Bi; Cui · 2026 · Circulation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion (ie, Na + /H + and Ca 2 + ) cycling underlies reduced cardiac contractility. The…
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Metadata source: PubMed · DOI 10.1161/circulationaha.126.079823