A Phase II Study of Potentiation of Pembrolizumab with Binimetinib and Bevacizumab in Refractory Microsatellite-Stable Colorectal Cancer
Robert W. Lentz; Tyler J. Friedrich; Patrick J. Blatchford; Kimberly R. Jordan; Todd M. Pitts; Hannah R. Robinson; S. Lindsey Davis; Sunnie S. Kim · 2024 · Clinical Cancer Research
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
PURPOSE: In this single-institution phase II investigator-initiated study, we assessed the ability of MAPK and VEGF pathway blockade to overcome resistance to immunotherapy in microsatellite-stable metastatic colorectal cancer (MSS mCRC).…
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Metadata source: OpenAlex · DOI 10.1158/1078-0432.ccr-24-0090