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Abandoned HypothesisOpen accessMedicine

Association of the TGF-beta1 polymorphism with primary open-angle glaucoma: a case-control study.

Derakhshan A; Zia MJ; Tavakkol Afshari J; Nikpoor AR; Shokoohi Rad S; Daneshvar R; Ghavami Shahri SH; Firozi J · 2026 · Medical hypothesis, discovery & innovation ophthalmology journal

WASTE classifies this as Abandoned Hypothesis · AI classification, approximate

A hypothesis was tested and not supported — a dead end worth knowing about before you pursue it.

Abstract (excerpt)

Background Primary open-angle glaucoma (POAG) is characterized by increased resistance to aqueous humor outflow. Transforming growth factor beta-1 (TGF-beta1) contributes to this resistance by promoting synthesis and remodeling of the…

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Metadata source: Europe PMC · DOI 10.51329/mehdiophthal1537