e-ISSN: Pending
Replication FailureOpen accessMedicine

Effects of Metformin on Cancer Survival Among Men Diagnosed with Advanced Prostate Cancer Treated with Androgen-Deprivation Therapy: Emulating a Target Trial.

Lopez DS; Polychronopoulou E; Abdelgadir O; Greenberg R; Cowell LG; Messiah SE; Kuo YF · 2025 · Cancers

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background/Objectives: Metformin is one of the most frequently used concomitant medications among prostate cancer (PCa) patients. However, the effects of metformin on all-cause and PCa-specific mortality among men diagnosed with…

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Metadata source: Europe PMC · DOI 10.3390/cancers17213579