Various Simulated Body Fluids Lead to Significant Differences in Collagen Tissue Engineering Scaffolds
Tomáš Suchý; Martin Bartoš; Radek Sedláček; Monika Šupová; Margit Žaloudková; Gražyna Simha Martynková; René Foltán · 2021 · Materials
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
This study aims to point out the main drawback with respect to the design of simulated body environments. Three media commonly used for the simulation of the identical body environment were selected, i.e., Kokubo's simulated body fluid that simulates the inorganic component of human blood plasma, human blood plasma, and phosphate buffer saline. A comparison was performed of the effects of the media on collagen scaffolds. The mechanical and structural effects of the media were determined via the application of compression mechanical tests, the determination of mass loss, and image and micro-CT
Abstract by Tomáš Suchý; Martin Bartoš; Radek Sedláček; Monika Šupová; Margit Žaloudková; Gražyna Simha Martynková; René Foltán, Materials (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/ma14164388