Low-dose oral pregabalin is not effective enough to control the acute post-thoracotomy pain
Swati Dogra ; Altaf Hussain Mir ; Suhail Sidiq ; Rohey Jan; Talib Khan ; Syed Amer Zahoor ; Hakeem Zubair Ashraf ; Shaqul Qamar Wani · 2025 · Asian Journal of Medical Sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Acute post-thoracotomy pain (APTP) is severe and can lead to various respiratory complications if left untreated. Epidural (Ep) analgesia is the gold standard for APTP relief. Aims and Objectives: The aims and objectives of this study were to study the impact of low-dose oral pregabalin 75 mg on APTP. Materials and Methods: 100 patients were randomized into two groups (Group P and C). The Group P, study group received pregabalin 75 mg per oral preoperatively and for 2 days postoperatively. Group C received no medication. All the patients received thoracic Ep as a standard practice.
Abstract by Swati Dogra ; Altaf Hussain Mir ; Suhail Sidiq ; Rohey Jan; Talib Khan ; Syed Amer Zahoor ; Hakeem Zubair Ashraf ; Shaqul Qamar Wani , Asian Journal of Medical Sciences (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI https://doi.org/10.71152/ajms.v16i5.4484