Emerging biologic frontiers for Sjogren’s syndrome: Unveiling novel approaches with emphasis on extra glandular pathology
Xiao Li; Maierhaba Maitiyaer; Qing Tan; Wen Hui Huang; Yü Liu; Zhi Ping Liu; Yue Qiang Wen; Yu Zheng · 2024 · Frontiers in Pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Primary Sjögren's Syndrome (pSS) is a complex autoimmune disorder characterized by exocrine gland dysfunction, leading to dry eyes and mouth. Despite growing interest in biologic therapies for pSS, FDA approval has proven challenging due to trial complications. This review addresses the absence of a molecular-target-based approach to biologic therapy development and highlights novel research on drug targets and clinical trials. A literature search identified potential pSS treatment targets and recent advances in molecular understanding. Overlooking extraglandular symptoms like fatigue and depr
Abstract by Xiao Li; Maierhaba Maitiyaer; Qing Tan; Wen Hui Huang; Yü Liu; Zhi Ping Liu; Yue Qiang Wen; Yu Zheng, Frontiers in Pharmacology (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fphar.2024.1377055