Aqueous and methanol extracts of Paullinia pinnata improve MSUc uptake in macrophages and in vitro antioxidant effects
Pius Pum Tseuguem; Télesphore Benoît Nguelefack; Elvine Pami Nguelefack-Mbuyo; Ines Diane Tchio Kenne; Judith Manialeu Pouadjeu; Basile Nganmegne Piegang · 2026 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Extracts of Paullinia pinnata have demonstrated therapeutic effects in monosodium urate (MSU)-induced gout in rats, notably by reducing inflammation and hyperalgesia, as well as enhancing antioxidant activity in vivo. However, their in vitro antioxidant potential and their effects on MSU-stimulated macrophages remain insufficiently explored. This study aims to investigate the in vitro antioxidant properties of P. pinnata, with a particular focus on MSU uptake in stimulated macrophages. The in vitro antioxidant activities of aqueous (AEPP) and methanolic (MEPP) extracts of P. pinnata l
Abstract by Pius Pum Tseuguem; Télesphore Benoît Nguelefack; Elvine Pami Nguelefack-Mbuyo; Ines Diane Tchio Kenne; Judith Manialeu Pouadjeu; Basile Nganmegne Piegang, Scientific Reports (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1038/s41598-026-48124-y