TNF-α antagonist alleviates muscular layer enlargement but does not prevent myenteric neuronal loss in the colon of streptozotocin-induced diabetic rats.
Sholikah TA; Septyaningtrias DE; Sumiwi YAA; Muthmainah M; Nyengaard JR; Susilowati R · 2025 · Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background this study aimed to examine the impact of a TNF-α antagonist on markers of neuronal death, the total number of myenteric neurons, and the volume of each colonic layer in diabetic rats. Methods thirty male rats were divided into…
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Metadata source: Europe PMC · DOI 10.1016/j.aanat.2025.152666