The effect of haemoglobin and blood transfusion on preterm infant gut perfusion and injury
Claire Howarth; Christian Mifsud; Christian Mifsud; Jayanta Banerjee; Simon Eaton; Terence Leung; Paul Fleming; Joan Morris · 2024 · Frontiers in Pediatrics
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
IntroductionThere is significant uncertainty regarding the role that anaemia or red blood cell transfusion (RBCT) plays in the development of gut injury in preterm infants. This study evaluated Near Infrared Spectroscopy (NIRS) together with a range of known biomarkers of gut inflammation to identify their relationship with anaemia and RBCT.MethodA prospective observational study of preterm infants born at <30 weeks gestation was conducted from birth until either 36 weeks post conceptional age or discharge home. Gut perfusion and biomarkers of gut injury were assessed weekly by: 60 min NIRS me
Abstract by Claire Howarth; Christian Mifsud; Christian Mifsud; Jayanta Banerjee; Simon Eaton; Terence Leung; Paul Fleming; Joan Morris, Frontiers in Pediatrics (2024) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fped.2024.1440537