Biological versus Technical Reliability of Epigenetic Clocks and Implications for Disease Prognosis and Intervention Response
Sehgal R; Borrus D; Gonzalez J; Markov Y; Higgins-Chen A · 2025 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
DNA methylation–based aging biomarkers, or epigenetic clocks, are increasingly used to estimate biological age and predict health outcomes. Their translational utility, however, depends not only on predictive accuracy but also on…
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Metadata source: Europe PMC · DOI 10.1101/2025.10.13.682176