Evaluation of antioxidant co-therapy for polymyxin B-associated nephrotoxicity and mortality: a real-World retrospective cohort study.
Qi J; Yin Z; Peng Y; Zhang F; Li Y; Xia X; Jia X · 2025 · Journal of pharmaceutical policy and practice
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Polymyxin B is increasingly used to treat infections caused by multidrug-resistant gram-negative bacteria; however, its widespread clinical use is hindered by the high incidence of nephrotoxicity. Antioxidants, such as vitamin…
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Metadata source: Europe PMC · DOI 10.1080/20523211.2025.2568673