Antibody-drug conjugates in gynecologic cancer: current landscape, clinical data, and emerging targets
Juan He; Mi Chen; Jia Li; Ying Wang · 2025 · International Journal of Gynecological Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Antibody-drug conjugates (ADCs) are an emerging class of targeted therapies that combine monoclonal antibodies with potent cytotoxic payloads, demonstrating significant potential in the treatment of gynecologic malignancies. By selectively targeting tumor-associated antigens, ADCs enable precise drug delivery while minimizing off-target toxicity. Currently, mirvetuximab soravtansine and tisotumab vedotin have been approved by the Food and Drug Administration for the treatment of folate receptor-alpha-positive, platinum-resistant ovarian cancer and recurrent cervical cancer, respectively, exhib
Abstract by Juan He; Mi Chen; Jia Li; Ying Wang, International Journal of Gynecological Cancer (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.ijgc.2025.101978