M2 macrophage-targeting peptide-modified liposomes enhance the uptake and antitumor efficacy of liposomal IFN-γ in mice with C26 colon carcinoma.
Kateh Shamshiri M; Vakili-Ghartavol R; Aiyelabegan HT; Asvar Z; Zare Marzouni H; Matbou Riahi M; Jaafari MR · 2025 · Cytokine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
While liposomes enhance the safety and pharmacokinetic profile of free drugs, they have not significantly improved therapeutic efficacy. To overcome this challenge, targeted depletion of tumor-associated macrophages (TAMs) shows…
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Metadata source: Europe PMC · DOI 10.1016/j.cyto.2025.156860