Phase 1 LITESPARK-001 study of belzutifan in participants with advanced solid tumors: Results of the glioblastoma expansion cohort.
Strowd RE; de la Fuente M; Bauer TM; Papadopoulos KP; Chen K; Perini RF; Liu Y; McDermott DF · 2026 · Neuro-oncology advances
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Recurrent isocitrate dehydrogenase (IDH) wild-type glioblastoma has no established standard-of-care treatment. Preclinical models have demonstrated that hypoxia-inducible factor-2 alpha (HIF-2α) contributes to stabilizing the hypoxic…
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Metadata source: Europe PMC · DOI 10.1093/noajnl/vdaf242