Negative / Null Result ReportOpen accessMedicine

Associations between CYP2C8 rs10509681 and rs11572080 gene polymorphisms and age-related macular degeneration

Rasa Liutkevičienė; Ramunė Sungailienė; Alvita Vilkevičiūtė; Loresa Kriaučiūnienė; Paulina Vaitkienė; Romanas Chaleckis; Vytenis Pranas Deltuva · 2017 · Acta Medica Lituanica

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background. Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in industrialized countries. Early symptoms of AMD include drusen and changes in retinal pigment epithelium. However, the etiology of AMD and drusen formation is not fully understood. Recent studies suggest that CYP2C8-related metabolic processes might play an important role in the development of AMD. The aim of our study is to investigate CYP2C8 rs10509681 and CYP2C8 rs11572080 genotype frequencies in patients with early AMD and to compare them with healthy controls. Materials and Methods.

Abstract by Rasa Liutkevičienė; Ramunė Sungailienė; Alvita Vilkevičiūtė; Loresa Kriaučiūnienė; Paulina Vaitkienė; Romanas Chaleckis; Vytenis Pranas Deltuva, Acta Medica Lituanica (2017) — licensed CC BY 4.0.

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