Novel Treatment Strategies for Hormone Receptor (HR)-Positive, HER2-Negative Metastatic Breast Cancer
Antonella Ferro; Michela Campora; A. Caldara; Delia De Lisi; M. Lorenzi; Sara Monteverdi; Raluca Mihai; Alessandra Bisio · 2024 · Journal of Clinical Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Estrogen receptor (ER)-positive breast cancer (BC) is the most common BC subtype. Endocrine therapy (ET) targeting ER signaling still remains the mainstay treatment option for hormone receptor (HR)-positive BC either in the early or in advanced setting, including different strategies, such as the suppression of estrogen production or directly blocking the ER pathway through SERMs—selective estrogen receptor modulators—or SERDs—selective estrogen receptor degraders. Nevertheless, the development of de novo or acquired endocrine resistance still remains challenging for oncologists. The use of no
Abstract by Antonella Ferro; Michela Campora; A. Caldara; Delia De Lisi; M. Lorenzi; Sara Monteverdi; Raluca Mihai; Alessandra Bisio, Journal of Clinical Medicine (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/jcm13123611