Cerebrospinal Fluid Biomarkers in Spinocerebellar Ataxia: A Pilot Study
Ashley M. Brouillette; Gülin Öz; Christopher M. Gómez · 2015 · Disease Markers
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Neurodegenerative diseases, including the spinocerebellar ataxias (SCA), would benefit from the identification of reliable biomarkers that could serve as disease subtype-specific and stage-specific indicators for the development and monitoring of treatments. We analyzed the cerebrospinal fluid (CSF) level of tau, α-synuclein, DJ-1, and glial fibrillary acidic protein (GFAP), proteins previously associated with neurodegenerative processes, in patients with the autosomal dominant SCA1, SCA2, and SCA6, and the sporadic disease multiple system atrophy, cerebellar type (MSA-C), compared with age-ma
Abstract by Ashley M. Brouillette; Gülin Öz; Christopher M. Gómez, Disease Markers (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1155/2015/413098