Epigallocatechin gallate (EGCG) partially prevents elastase-induced mechanical and microstructural changes in the mouse ascending aorta in vitro.
Castro LA; Chen DE; O'Scannlain A; Dwivedi KK; Kailash KA; Rother J; Crandall CL; Roth RA · 2026 · Journal of the mechanical behavior of biomedical materials
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Elastic fibers are critical for proper mechanical function of large arteries such as the aorta. Fragmentation, degradation, or reduced amounts of elastic fibers are associated with aortic diseases such as stiffening-induced hypertension…
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Metadata source: Europe PMC · DOI 10.1016/j.jmbbm.2026.107340