The effect of SIRT1 knockdown on the gene expression of CoQ10 biosynthetic enzymes.
Okuizumi R; Maruyama S; Okamoto M; Fujisawa A; Yamamoto Y; Kashiba M · 2026 · Journal of clinical biochemistry and nutrition
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Coenzyme Q10 is a lipid-soluble antioxidant essential for the mitochondrial electron transport chain. Its concentration in the body decreases with age. The biosynthesis of coenzyme Q10 involves enzymes coq1 (PDSS1, PDSS2) through coq9,…
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Metadata source: Europe PMC · DOI 10.3164/jcbn.24-239