Closed-loop modulation of local slow oscillations in human NREM sleep
Simon Ruch; Flavio Jean Schmidig; Leona Knüsel; Katharina Henke · 2022 · NeuroImage
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Slow-wave sleep is the deep non-rapid eye-movement (NREM) sleep stage that is most relevant for the recuperative function of sleep. Its defining property is the presence of slow oscillations (<2 Hz) in the scalp electroencephalogram (EEG). Slow oscillations are generated by a synchronous back and forth between highly active UP-states and silent DOWN-states in neocortical neurons. Growing evidence suggests that closed-loop sensory stimulation targeted at UP-states of EEG-defined slow oscillations can enhance the slow oscillatory activity, increase sleep depth, and boost sleep's recuperative fun
Abstract by Simon Ruch; Flavio Jean Schmidig; Leona Knüsel; Katharina Henke, NeuroImage (2022) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.neuroimage.2022.119682