Estimated Glomerular Filtration Rate Correlates Poorly with Four-Hour Creatinine Clearance in Critically Ill Patients with Acute Kidney Injury
Christopher J. Kirwan; Barbara J. Philips; Iain A. M. MacPhee · 2013 · Critical Care Research and Practice
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is needed, and some published data suggest that equations based on serum creatinine that estimate glomerular filtration rate (eGFR) can provide this. In addition, incorporating serum cystatin C concentration into estimates of GFR may improve their accuracy, but no eGFR equations are validated in critically ill patients with AKI. Aim. This study t
Abstract by Christopher J. Kirwan; Barbara J. Philips; Iain A. M. MacPhee, Critical Care Research and Practice (2013) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1155/2013/406075