Changes in functional connectivity of the default mode network and thalamus may be a therapeutic mechanism for the treatment of major depressive disorder with vortioxetine.
Song Z; Wang H; Jin M; Liu J; Yuan L; Zhu Y; Lian J; Xu X · 2026 · Psychiatry research. Neuroimaging
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
This study investigates the pathogenic mechanisms underlying major depressive disorder (MDD) and the therapeutic mechanisms of vortioxetine in treatment-naive, first-episode MDD patients. 22 treatment -naive, first-episode MDD patients and…
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Metadata source: Europe PMC · DOI 10.1016/j.pscychresns.2026.112199