Multiple sclerosis: molecular pathogenesis and therapeutic intervention
Imane Boutitah-Benyaich; Herena Eixarch; Javier Villacieros‐Álvarez; Arnau Hervera; Álvaro Cobo‐Calvo; Xavier Montalbán; Carmen Espejo · 2025 · Signal Transduction and Targeted Therapy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Multiple sclerosis is a chronic immune-mediated disorder of the central nervous system characterized by demyelination, axonal loss, and neuroinflammation, culminating in progressive neurological disability. Despite significant advances in understanding its immunopathogenesis, current immunotherapies remain limited in their ability to halt disease progression, making multiple sclerosis incurable and highlighting the critical need for novel therapeutic strategies. Antigen-specific immunotherapy represents a groundbreaking approach that aims to restore immune tolerance to myelin-derived antigens
Abstract by Imane Boutitah-Benyaich; Herena Eixarch; Javier Villacieros‐Álvarez; Arnau Hervera; Álvaro Cobo‐Calvo; Xavier Montalbán; Carmen Espejo, Signal Transduction and Targeted Therapy (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41392-025-02415-4