Negative / Null Result ReportOpen accessMedicine· cited by 43

Genetic characterization of an insect-specific flavivirus isolated from Culex theileri mosquitoes collected in southern Portugal

Ricardo Parreira; Shelley Cook; Ângela Celis de Almeida Lopes; António Matos; António Paulo Gouveia de Almeida; J. Piedade; Aida Esteves · 2012 · Virus Research

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

The finding, in one line

“The virus, designated CTFV, for Culex theileri flavivirus, was isolated in the C6/36 Stegomyia albopicta (=Aedes albopictus) cell line, and failed to replicate in vertebrate (Vero) cells in common with other ISFs.”

Abstract

We describe the full genetic characterization of an insect-specific flavivirus (ISF) from Culex theileri (Theobald) mosquitoes collected in Portugal. This represents the first isolation and full characterization of an ISF from Portuguese mosquitoes. The virus, designated CTFV, for Culex theileri flavivirus, was isolated in the C6/36 Stegomyia albopicta (=Aedes albopictus) cell line, and failed to replicate in vertebrate (Vero) cells in common with other ISFs. The CTFV genome encodes a single polyprotein with 3357 residues showing all the features expected for those of flaviviruses. Phylogeneti

Abstract by Ricardo Parreira; Shelley Cook; Ângela Celis de Almeida Lopes; António Matos; António Paulo Gouveia de Almeida; J. Piedade; Aida Esteves, Virus Research (2012) — licensed CC BY 4.0.

Read the full paper (open access)