SAFFRON-301: a randomised phase III study of sitravatinib in combination with tislelizumab in patients with locally advanced or metastatic non-small cell lung cancer.
Zhou Q; Gao B; Hu J; Zhao J; Wang M; He K; Zhang W; Liu C · 2026 · BMJ oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Many patients with non-small cell lung cancer (NSCLC) have tumours that are either refractory or develop resistance following an initial response to anti-programmed cell death protein (ligand)-1 (PD-(L)1)-based treatment,…
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Metadata source: Europe PMC · DOI 10.1136/bmjonc-2025-000890