GSDM gene polymorphisms regulate the IgE level in asthmatic patients.
Amer Imraish; Tuqa Abu-Thiab; Tareq Alhindi; Malek Zihlif · 2022 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background Gasdermin A (GSDMA) and gasdermin B (GSDMB) have been associated with childhood and adult asthma in many populations including the Jordanian population. It is also known that IgE plays a crucial role in various allergic disorders, such elevated levels of total serum IgE were detected in asthma and allergic rhinitis. IgE immunoglobulin is responsible for the release of numerous inflammatory mediators, such as histamine and prostaglandins, from mast cells in asthmatic patients. Objective In this study, single nucleotide polymorphisms of GSDMA (rs7212938, T/G) and GSDMB (rs7216389, T/C
Abstract by Amer Imraish; Tuqa Abu-Thiab; Tareq Alhindi; Malek Zihlif, PLoS ONE (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1371/journal.pone.0274951