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Negative / Null Result ReportOpen accessAgricultural and Biological Sciences· cited by 30

A viroid-derived system to produce large amounts of recombinant RNA in Escherichia coli

José‐Antonio Daròs; Verónica Aragonés; Teresa Cordero · 2018 · Scientific Reports

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Viruses have been engineered into useful biotechnological tools for gene therapy or to induce the synthesis of products of interest, such as therapeutic proteins and vaccines, in animal and fungal cells, bacteria or plants. Viroids are a particular class of infectious agents of higher plants that exclusively consist of a small non-protein-coding circular RNA molecule. In the same way as viruses have been transformed into useful biotechnological devices, can viroids be converted into beneficial tools? We show herein that, by expressing Eggplant latent viroid (ELVd) derived RNAs in Escherichia c

Abstract by José‐Antonio Daròs; Verónica Aragonés; Teresa Cordero, Scientific Reports (2018) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1038/s41598-018-20314-3