Management of Recurrence in Ovarian Cancer—The Role of Surgery and HIPEC with Relevance to BRCA Testing in a PARPi Landscape
Mathilde Duchon; Raj Naik; Fabrice R Lecuru; Gwénaël Ferron; Caroline Cornou; Sabrina Madad Zadeh; Christophe Pomel · 2025 · Cancers
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: The surgical and medical management of recurrent ovarian cancer is complex and requires a personalized approach based on several factors, including the timing of recurrence, the patient’s performance status, previous treatment regimens, and the tumor’s histology and molecular characteristics. Objectives: Five randomized trials—GOG-0213, DESKTOP III, SOC 1, HORSE, and CHIPOR—have been conducted and shed light on our practice. Results: Both the DESKTOP III and the SOC 1 trials support the benefit of secondary surgery. The GOG-0213 trial, however, did not show an overall survival bene
Abstract by Mathilde Duchon; Raj Naik; Fabrice R Lecuru; Gwénaël Ferron; Caroline Cornou; Sabrina Madad Zadeh; Christophe Pomel, Cancers (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/cancers17040646