Phase II Trial of Pemetrexed and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer
Athanassios Argiris; Michalis V. Karamouzis; William E. Gooding; Barton F. Branstetter; Shilong Zhong; Luis E. Raez; P. Savvides; Marjorie Romkes · 2011 · Journal of Clinical Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
PURPOSE: We hypothesized that bevacizumab, a monoclonal antibody against vascular endothelial growth factor (VEGF), will potentiate the activity of pemetrexed, a multitargeted antifolate, in squamous cell carcinoma of the head and neck…
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Metadata source: OpenAlex · DOI 10.1200/jco.2010.33.3591