Evaluating the role of high-dose intravenous thiamine supplementation for lactate clearance in patients with cirrhosis and sepsis.
Ali R; Yazdi A; Collins K; Guffey D; Wu TD; Kessinger R; Omranian A; Vallabh M · 2026 · International journal of critical illness and injury science
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Thiamine is a vitamin that plays a role in lactate clearance. Patients with sepsis may present with elevated lactate, and also in cirrhosis, as lactate is hepatically metabolized. Prior studies showed mixed results regarding the…
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Metadata source: Europe PMC · DOI 10.4103/ijciis.ijciis_124_25