TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer
Bogang Wu; Win Thant; Elena Bitman; T. Liu; Jie Liu; Eleftherios I. Paschalis; Bidish K. Patel; Cole Nawrocki · 2026 · Journal for ImmunoTherapy of Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
ABSTRACT Background Immune exclusion inhibits anti-tumor immunity and response to immunotherapy, but its mechanisms remain poorly defined. In triple-negative breast cancer (TNBC), an aggressive and generally immune-rich subtype, an…
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Metadata source: OpenAlex · DOI 10.1136/jitc-2025-012265