Computationally efficient whole-genome quantile regression at biobank scale.
Wang F; Wang C; Wang T; Masala M; Fiorillo E; Devoto M; Cucca F; Ionita-Laza I · 2025 · Proceedings of the National Academy of Sciences of the United States of America
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Genotype-phenotype associations can be context-dependent and dynamic in nature leading to heterogeneity of genetic effects across different parts of the phenotype distribution. Quantile regression, an alternative to linear regression for…
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Metadata source: Europe PMC · DOI 10.1073/pnas.2513007122