Association of Polygenic Risk Scores With Aortic Valve Calcium: The Multi-Ethnic Study of Atherosclerosis.
Whelton SP; Yao J; Clish C; Wood AC; Taylor KD; Blaha MJ; Budoff M; Marrero N · 2026 · Journal of the American Heart Association
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Aortic valve calcification (AVC) is the primary process leading to aortic stenosis. We examined whether polygenic risk scores (PRS) are associated with AVC beyond traditional atherosclerotic cardiovascular disease risk factors.…
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Metadata source: Europe PMC · DOI 10.1161/jaha.124.040064