Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study
Sèverine Sabia; Aline Dugravot; Jean‐François Dartigues; Jessica Abell; Alexis Elbaz; Mika Kivimäki; Archana Singh‐Manoux · 2017 · BMJ
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“This study found no evidence of a neuroprotective effect of physical activity.”
Abstract
This study found no evidence of a neuroprotective effect of physical activity. Previous findings showing a lower risk of dementia in physically active people may be attributable to reverse causation-that is, due to a decline in physical activity levels in the preclinical phase of dementia.
Abstract by Sèverine Sabia; Aline Dugravot; Jean‐François Dartigues; Jessica Abell; Alexis Elbaz; Mika Kivimäki; Archana Singh‐Manoux, BMJ (2017) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
Negative / Null Result ReportDuodenal Infusion of Donor Feces for Recurrent Clostridium difficile
Negative / Null Result ReportStenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis
Negative / Null Result ReportEffects of Combination Lipid Therapy in Type 2 Diabetes Mellitus
Replication FailureA Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Negative / Null Result ReportSpironolactone for Heart Failure with Preserved Ejection Fraction
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1136/bmj.j2709