Evidence for contribution of common genetic variants within chromosome 8p21.2-8p21.1 to restricted and repetitive behaviors in autism spectrum disorders
Tao Yu; Hui Gao; Benjamin Ackerman; Wei Guo; David Saffen; Yin Yao Shugart · 2016 · BMC Genomics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Restricted and Repetitive Behaviors (RRB), one of the core symptom categories for Autism Spectrum Disorders (ASD), comprises heterogeneous groups of behaviors. Previous research indicates that there are two or more factors (subcategories) within the RRB domain. In an effort to identify common variants associated with RRB, we have carried out a genome-wide association study (GWAS) using the Autism Genetic Resource Exchange (AGRE) dataset (n = 1,335, all ASD probands of European ancestry) for each identified RRB subcategory, while allowing for comparisons of associated single nucleot
Abstract by Tao Yu; Hui Gao; Benjamin Ackerman; Wei Guo; David Saffen; Yin Yao Shugart, BMC Genomics (2016) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12864-016-2475-y