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Negative / Null Result ReportMedicine

Plasma chaperone-mediated autophagy associated protein HSPA8 combined with white matter hyperintensities serves as the predictive marker of early-stage Alzheimer's disease.

Yan; Liang; Zhou; Hong; Li; Wang; Huang; Xiao · 2026 · Frontiers in aging neuroscience

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

The relationship between plasma chaperone-related autophagy proteins and white matter hyperintensity (WMH) in Alzheimer's disease (AD) remains unclear. We employed 4D-DIA proteomics to identify plasma protein changes, and evaluated the…

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Metadata source: PubMed · DOI 10.3389/fnagi.2026.1753692