Evaluation of standard and modified two-tiered testing algorithms using well-characterized early Lyme disease samples.
Horn EJ; Menefee B; Schotthoefer AM; Dempsey G; McArdle M; Weber AF; De Luca C; Pritt BS · 2026 · Journal of clinical microbiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Current laboratory testing for Lyme disease (LD) relies on serology. We evaluated the performance of standard two-tiered testing (STTT) and modified two-tiered testing (MTTT) algorithms using samples obtained from well-characterized…
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Metadata source: Europe PMC · DOI 10.1128/jcm.01187-25