TRAF1/C5but NotPTPRCVariants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy
Helena Canhão; Ana Maria Rodrigues; María José Santos; Diana Carmona-Fernandes; Bruno Filipe Bettencourt; Jing Cui; Fabiana Lucena Rocha; José António Pereira da Silva · 2015 · BioMed Research International
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: The aim of our work was to replicate, in a Southern European population, the association reported in Northern populations between PTPRC locus and response to anti-tumor necrosis factor (anti-TNF) treatment in rheumatoid arthritis (RA). We also looked at associations between five RA risk alleles and treatment response. METHODS: We evaluated associations between anti-TNF treatment responses assessed by DAS28 change and by EULAR response at six months in 383 Portuguese patients. Univariate and multivariate linear and logistic regression analyses were performed. In a second step to con
Abstract by Helena Canhão; Ana Maria Rodrigues; María José Santos; Diana Carmona-Fernandes; Bruno Filipe Bettencourt; Jing Cui; Fabiana Lucena Rocha; José António Pereira da Silva, BioMed Research International (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1155/2015/490295