Negative / Null Result ReportOpen accessMedicine

Cycling GLP-1 receptor agonist treatment induces therapeutic resistance and increased adiposity.

Son AJ; Rapp E; Wiezorek A; Leung MG; Banerjee RR; Leung TH · 2026 · JCI insight

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Stopping and restarting GLP-1 weight-loss drugs in mice made them less effective over time and increased fat gain compared with continuous treatment.

Excerpt shown for reference under fair use — read the full paper at the publisher.

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Metadata source: Europe PMC · DOI 10.1172/jci.insight.205174