e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

Variations of five eIF4E genes across cassava accessions exhibiting tolerant and susceptible responses to cassava brown streak disease.

Shanshan Shi; Xiuchun Zhang; M Alejandra Mandel; Peng Zhang; Yuliang Zhang; Morag Ferguson; Teddy Amuge; Steve Rounsley · 2017 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Cassava (Manihot esculenta) is an important tropical subsistence crop that is severely affected by cassava brown streak disease (CBSD) in East Africa. The disease is caused by Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Both have a (+)-sense single-stranded RNA genome with a 5' covalently-linked viral protein, which functionally resembles the cap structure of mRNA, binds to eukaryotic translation initiation factor 4E (eIF4E) or its analogues, and then enable the translation of viral genomic RNA in host cells. To characterize cassava eIF4Es and their potent

Abstract by Shanshan Shi; Xiuchun Zhang; M Alejandra Mandel; Peng Zhang; Yuliang Zhang; Morag Ferguson; Teddy Amuge; Steve Rounsley, PLoS ONE (2017) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1371/journal.pone.0181998