Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling.
Lerma-Clavero A; Kopsida M; Arendt N; Lennernäs H; Sjöblom M; Heindryckx F · 2026 · FEBS open bio
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The unfolded protein response (UPR) plays an important role in tumor progression and cellular stress adaptation. In hepatocellular carcinoma (HCC), pharmacological inhibition of the protein kinase R-like endoplasmic reticulum kinase (PERK)…
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Metadata source: Europe PMC · DOI 10.1002/2211-5463.70252