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Negative / Null Result ReportOpen accessMedicine· cited by 27

Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery

Dae-Sang Lee; Mi Yeon Lee; Chi-Min Park; Dong‐Ik Kim; Young-Wook Kim; Yang‐Jin Park · 2018 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

The finding, in one line

The preoperative statin exposure was not associated with reduced delirium in the univariate analysis.

Abstract

Delirium is a common complication of vascular surgery. The protective effect of preoperative statins on delirium after vascular surgery is controversial. The authors hypothesized that preoperative statin administration would decrease the incidence of delirium after vascular surgery. From May 2010 to May 2015, 1,132 patients underwent vascular surgery. Postoperative delirium was diagnosed from patients' medical records. The incidence of delirium was 11.5%. The preoperative statin exposure was not associated with reduced delirium in the univariate analysis. After adjusting for covariates, preope

Abstract by Dae-Sang Lee; Mi Yeon Lee; Chi-Min Park; Dong‐Ik Kim; Young-Wook Kim; Yang‐Jin Park, PLoS ONE (2018) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0192841