Distinguishing the Central Drive to Tremor in Parkinson's Disease and Essential Tremor
John‐Stuart Brittain; Hayriye Cagnan; Arpan R. Mehta; Tabish A. Saifee; Mark J. Edwards; Peter Brown · 2015 · Journal of Neuroscience
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Parkinson's disease (PD) and essential tremor (ET) are the two most common movement disorders. Both have been associated with similar patterns of network activation leading to the suggestion that they may result from similar network dysfunction, specifically involving the cerebellum. Here, we demonstrate that parkinsonian tremors and ETs result from distinct patterns of interactions between neural oscillators. These patterns are reflected in the tremors' derived frequency tolerance, a novel measure readily attainable from bedside accelerometry. Frequency tolerance characterizes the temporal ev
Abstract by John‐Stuart Brittain; Hayriye Cagnan; Arpan R. Mehta; Tabish A. Saifee; Mark J. Edwards; Peter Brown, Journal of Neuroscience (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1523/jneurosci.3768-14.2015